Natural Peptide Antibiotics from Tunicates: Structures, Functions and Potential Uses
نویسندگان
چکیده
منابع مشابه
Natural Peptide antibiotics from tunicates: structures, functions and potential uses.
Because tunicates rely on innate immunity, their hemocytes are important contributors to host defense. Styela clava, a solitary ascidian, have eight hemocyte subtypes. Extracts of their total hemocyte population contained multiple small (2-4 kDa) antimicrobial peptides. When purified, these fell into two distinct families that were named styelins and clavanins.Styelins A-E are phenylalanine-ric...
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As is well recognized in the medical profession, the emergence of antibiotic-resistant bacteria creates serious public health problems. Most obviously, it makes it difficult to treat once easily cured infections, such as staph. It also increases the chances a patient will get an infection during a hospital stay. According to the Centers for Disease Control and Prevention, almost two million pat...
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The constantly growing resistance of microbes to drugs and other substances which fight microbial infections leads to search for new antimicrobial substances. Among substances which attract the scientists attention are antimicrobial peptides. Such compounds are quite common in nature and belong to the most important elements of the innate immune system of all living organisms. Numerous antimicr...
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INTRODUCTION............ 449 PROPERTIES OF PEPTIDE ANTIBIOTICS 449 FORMATION OF ANTIBIOTICS IN RELATION TO GROWTH ...... ............ 450 CELL-FREE SYNTHESIS OF PEPTIDE ANTIBIOTICS ...... .................. 451 ENZYMATIC SYNTHESIS OF GRAMICIDIN S ........ ......................... 451 ENZYMATIC FORMATION OF TYROCIDINE ........ ......................... 453 LINEAR GRAMICIDINS ......................
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ژورنال
عنوان ژورنال: Integrative and Comparative Biology
سال: 2003
ISSN: 1540-7063,1557-7023
DOI: 10.1093/icb/43.2.313